| Light Scattering
Detectors |
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| LT-Evaporative Light Scattering Detection |
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The Sedex range of detectors sets the standard of LT-ELSD for Liquid
Chromatography. The unique design for low temperature (LT) operation
guarantees for the highest sensitivity. Another effect is that it
is gentle to thermally labile compounds. Sedex LT-ELSD detects compounds
that are missed by other detectors and provides universal detection
for HPLC, micro-HPLC, SFC, GPC, GPEC, CCC and high temperature GPC
systems. It is not dependent on the presence or absence of chromophores,
fluorophores or electronegative groups. Any non-volatile analyte
can be detected and gradient elution can be employed to optimise
the separation. This detector can be used in conjunction with mass
spectrometry to provide a complete description of the sample.
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| SEDEX 85 LT-ELSD The Performance
Leader |
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The new Visually Enhanced SEDEX 85 LT-ELSD employs the most
advanced technology to provide the highest sensitivity, efficiency
and reproducibility of all ELS detectors in the market. This powerful
and versatile instrument can be used with any conventional HPLC,
from micro to preparative, due to the use of four specific nebulisers.
In addition, it is optimized to meet the requirements of ultra fast
liquid chromatography including Ultra High Performance Liquid Chromatography
(U-HPLC), High Temperature Liquid Chromatography (HTLC) and µ-HTLC.
For ì-HTLC, a patented cell has been designed to provide
the lowest dispersion and the best peak shape. As an example of
the power of the system, the SEDEX 85 can measure sub-one second
peak widths with data rate up to 100Hz.
As a true mass detector, calibration using SEDEX 85 LT-ELSD
is straightforward and consistent in responses with variations below
10% between compounds having identical concentrations and belonging
to the same chemical class. In addition, linearity over 3 orders
of magnitude can be easily achieved using the log-log coordinates
of the general equation A=a.mb.
Other equations such as secondorder or third-order polynomial equations
can also provide excellent quantitative results with correlation
coefficients nearly equal to 1.
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The new SEDEX 85LT combines total remote control with unprecedented
sensitivity. This smaller, stackable unit occupies only 25 cm of
bench space. Full SOP protocols are provided for GLP compliance
and validation procedures. Sophisticated, yet easy to use the SEDEX
85 is ready to detect in two simple steps:
SET
TEMPERATURE - SET GAIN
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Features
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Benefits
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Improved optical head design
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Lower limits of detection 100pg sensitivity
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Enhanced digital signal processing
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Minimizes peak broadening
Improves Signal/Noise ratio
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Patended Gas Supported Focusing (GSF)
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Optimizes detection
Reduces maintenance
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Option of four inter-changeable nebulizers
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Assures synergy with HPLC methods
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Programmable gain and temperature
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Optimizes sensitivity and user control
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THE SUPERB SENSITIVITY OF THE SEDEX
85
is demonstrated by an HPLC/LT-ELSD
Chromatogram of a 5µg Ethylene Glycol Injected sample
LOD=13ng
Drift tube temperature: 32°C
Mobile phase: 100% Water
Flow rate: 1ml/min
More applications...
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EXPANDED SOFTWARE FEATURES FOR HIGH THROUGHPUT REQUIREMENTS
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- New remote power-down control extends
life of optics and reduces costs
- Automatic gas shut-off at end of run prevents
waste
- Programmable operating parameters and
events are amenable to automation
- Password-protected, full system log supports
GLP compliance
- Storage of analytical methods saves operator
time
- Control of up to 16 SEDEX Detectors from
one workstation
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| Cat# |
SEDEX 85 LT-ELSD |
| 85000 |
HPLC Version, 230V |
| 85300 |
HPLC Low Flow Version, 230V |
| 85400 |
CC Version, 230V |
| 85600 |
micro HPLC Version, 230V |
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| NEW SEDEX
80 LT for Routine Applications |
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SEDEX 80 LT-ELSD combines high sensitivity, reliability and
accuarcy for your analyses, using the thanks to unrivalled SEDEX
Low Temperature technology. This detector presents a new Visually
Enhanced design and a number of outstanding innovations providing
the best optical and electronic benefits at a very competitive
price.
Two different nebulizers arev available to optimize the sensitivity
and resolution at HPLC flow rates from 100µl/min to 5ml/min
The SEDEX 80 LT-ELSD is a user-friendly and meets the requirements
of any HPLC system and application. In addition, the detector features
programmable power-down methods and optimized controls.
| Cat# |
SEDEX 80LT-ELSD |
| 80000 |
HPLC Version, 230V |
| 80400 |
CC Version, 230V |
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| SEDEX 75 LT-ELSD, the Reference Detector |
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- More than 2000 Sedex 75 are employed
in the field today.
- Includes Low Temperature technology
and patented GSF (Gas Supported Focusing).
- Four specific nebulizers are available
to optimize sensitivity and resolution at HPLC flow rates from
5ìL/min to 5mL/min.
- Easy to use and compatible with
all HPLC systems.
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Cat#
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SEDEX 75 LT-ELSD
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75000
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HPLC Version, 230V
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75200
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HPLC/SFC Version, 230V
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75300
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HPLC Low Flow Version, 230V
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75400
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CC Version, 230V
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75600
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micro HPLC Version, 230V
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| SEDEX NEBULIZER OPTIONS |
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| Learn more about light scattering principle
here... |
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| SEDEX 754 Parallel 4-Channel ELS-detection |
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Sedex 754 maximize sensitivity, efficiency and throughput of multiple
HPLC systems for Combinatorial Chemistry. Sedex 754 consists of
4 independent detectors operated in parallel. Each detector is controlled
from a common keypad and display or from a PC. The Sedex 754 reduces
the space that is needed per channel. It includes all the benefits
of our single channel Sedex 75. It has a superb sensitivity and
narrow peaks
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Sedex
754 Nebulizers |
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| Cat# |
Description |
| 04-754000 |
SEDEX 754 LT-ELSD, Multichannel |
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SEDEX 75LT |
SEDEX 80LT |
SEDEX 85LT |
| DATA |
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Detection
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Photomultiplier Tube
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Photomultiplier Tube |
Photomultiplier Tube |
| Light Source |
Halogen Lamp |
LED(470nm)
Elapsed Time Counter |
LED(470nm)
Elapsed Time Counter
Normalization |
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Temperature Range
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Ambient to 100°C
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Ambient to 100°C |
Ambient to 100°C
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Nebulizer
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4 options: Cappillary, Low Flow, HPLC, CC |
2 options: HPLC, CC |
4 options: Cappillary, Low Flow, HPLC, CC
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| Eluent Flow Rate |
5µl/min to 5ml/min |
100µl/min to 5ml/min |
5µl/min to 5ml/min |
| DATA |
| Analog Output |
0 - 1V |
0 - 1V |
0 - 1V
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Gain Settings
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211 (2048) |
211 (2048) |
211 (2048) |
| Filter |
Time Constant
(None, Medium, High) |
Moving Average
(0 - 10s) |
Moving Average
(0 - 10s) |
| Data Rate |
N/A |
40Hz |
100Hz
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| COMMUNICATION |
| Selection & Display |
7-Segments Display and Keypad
Windows based PC control |
Liquid Cristal Display And Keypad |
Liquid Cristal Display And Keypad
Windows based PC control |
| Event |
Contact closure for auto-zero |
Contact closure for ready, auto-zero |
Contact closure for ready, auto-zero |
| Power-down Methods |
N/A |
Shut-off: Gas, LED, Heating and/or PMT. Cleaning
Mode |
Shut-off: Gas, LED, Heating and/or PMT. Cleaning
Mode |
| Computer Interface |
RS232 |
RS232 |
RS232 |
| Software |
Option |
Option |
Bundled - Control of all the parameters
(Windows 9x, NT, 2000, XP) |
| GLP Compliance |
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Audit trail - Password - Admin. mode |
| EXTERNAL REQUIRMENTS |
| Power |
230V/50Hz 1.7Amp
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230V/50Hz 1.7Amp |
230V/50Hz 1.7Amp
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Gas Pressure
(Nitrtogen or Air)
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3.5 bars (51psi) |
3.5 bars (51psi) |
3.5 bars (51psi) |
| Dimension |
360mm (14.1")W
504mm (19.8"))H
500mm (19.7")D |
250mm (10")W
480mm (18"))H
550mm (22")D |
250mm (10")W
480mm (18"))H
550mm (22")D |
| Weight |
20kg (44lbs) |
18.5kg (40lbs) |
18.5kg (40lbs) |
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